Dr Fong Lai Yen
journal article
- Lai Yen Fong, Hee Yang Derrick Cheow, Chin Theng Ng, Yoke Keong Yong, Yang Mooi Lim, "A new insight into cardiovascular protective potentials of hydroxylated xanthones", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, Elsevier, Volume 296, Issue 11783, pp 1-15, May 2025 (ISSN: 0223-5234).
- Zainudin N, Ng CT, Fong LY, Yong YK, Hakim MN, "Anti-proliferative effects of Cu(Phen)(C-dimethylglycine)NO3 on HT-29 and A2780 cancer cell lines: a potential chemotherapeutic approach", Asian journal of pharmaceutical and clinical research, Innovare Academic Sciences, Volume 18, Issue 6, pp 76-80, May 2025 (ISSN: 0974-2441).
- Wong CH, Chew CH, Fong LY, Choo QC, "Lauric Acid Improves Insulin Resistance State in Diet-induced Obese Mice", Journal of Advanced Research in Micro and Nano Engineering, Semarak Ilmu, Volume 35, Issue 1, pp 45-58, May 2025 (ISSN: 2756-8210).
- Chin Theng Ng, Lai Yen Fong, Jun Jie Tan, Muhammad Nazrul Hakim Abdullah, "Endothelial barrier disruptive effect of IFN-Ƴ and TNF-α: Synergism of pro-inflammatory cytokines", CYTOKINE, Elsevier, Volume 190, pp 15692, March 2025 (ISSN: 1043-4666).
- Ragavan O,, Lim JX,, Abdullah MNH, Fong LY, Lim V, Tan JJ,, "Deciphering the potential mechanisms of
Alternanthera sessilis red against atherosclerosis
by integrating LC-MS/MS method, network
pharmacology and molecular docking approaches", Journal of Biologically Active Products from Nature, Taylor & Francis, Volume 14, pp 647-681, December 2024 (ISSN: 2231-1874).
- Ragavan O, Abdullah MNH, Fong LY, Lim V, Yong YK, "Zinc Nanostructure: A Short Review on Phytochemicals-Mediated Biogenic Synthesis and Its Anti-Inflammatory Effects", JOURNAL OF CLUSTER SCIENCE, Springer, Volume 35, pp 2213-2230, August 2024 (ISSN: 1572-8862).
- Chin Theng Ng, Lai Yen Fong, Muhammad Nazrul Hakim Abdullah, "Interferon-gamma (IFN-γ): Reviewing its mechanisms and signaling pathways on the regulation of endothelial barrier function", CYTOKINE, Elsevier (Article ID 156208), Volume 166, pp 1-7, April 2023 (ISSN: 1043-4666).
- Nur Nadia Mohd Razali, Soek Sin Teh, Siau Hui Mah, Yoke Keong Yong, Chin Theng Ng, "Protective Effects of Alternanthera sessilis Ethanolic
Extract against TNF-α or H2O2-Induced Endothelial Activation
in Human Aortic Endothelial Cells", Evidence-based Complementary and Alternative Medicine, Hindawi (Volume 2022, Article ID 8738435, 12 pages), Volume 2022, pp 1-12, February 2022 (ISSN: 1741-427X).
- Nur Aqilah Kamaruddin, Muhammad Nazrul Hakim Abdullah, Jun Jie Tan, Vuanghao Lim, Lai Yen Fong et al., "Vascular Protective Effect and Its Possible Mechanism of Action on Selected Active Phytocompounds: A Review", Evidence-based Complementary and Alternative Medicine, Hindawi (Article ID 3311228), Volume 2022, pp 1-17, April 2022 (ISSN: 1741-427X).
- Ahmad Firdaus bin Abdul Khalid, Chin Theng Ng, Lai Yen Fong, Jun Jie Tan, Fahmi bin Yakop et al, "Malaysian Tualang Honey Suppresses the Angiogenic Events in Endothelial Cells Induced by Vascular Endothelial Growth Factor", Sains Malaysiana, Universiti Kebangsaan Malaysia, Volume 51, pp 815-822, March 2022 (ISSN: 0126-6039).
- Tanimale DR, Sahgal G, George SD, Fong LY, Asem M, "Antioxidant and Anti-inflammatory Properties of Nyctanthes Arbor-tristis Leaf Extracts in High Glucose-induced Sprague Dawley Rats", NeuroQuantology, AnKa Publisher, Volume 20, pp 5236-5247, July 2022 (ISSN: 1303-5150).
- Ooi KX, Subramaniam M, Fong LY, Goh HH, Khoo SBA, "Apoptotic and Cytostatic Actions of Maslinic Acid in Colorectal Cancer Cell Lines Through Possible IKK-β Inhibition", Asian Pacific Journal of Tropical Biomedicine, Wolters Kluwer, Volume 11, pp 122-131, January 2021 (ISSN: 2221-1691).
- Binti Kamaruddin NA, Fong LY, Tan JJ, Abdullah MNH, et al, "Cytoprotective role of omentin against oxidative stress-induced vascular endothelial cells injury", MOLECULES, MDPI, Volume 25, pp 2534, May 2020 (ISSN: 1420-3049).
- Kow ASF, Fong LY,, Khoo LW, Tan JW, Tham CL, "Clinacanthus nutans Aqueous Extract Suppresses the Release of Histamine and β‑Hexosaminidase in in-vitro Model of IgE‑Mediated Mast Cell Degranulation", Pharmacognosy Magazine, PhCog.net, Volume 16, pp 400-408, June 2020 (ISSN: 0973-1296).
- Nur Nadia Mohd Razali, Ng Chin Theng, Fong Lai Yen, "Cardiovascular protective effects of Centella asiatica and its triterpenes: A review", PLANTA MEDICA, Thieme, Volume 85, pp 1203-1215, October 2019 (ISSN: 0032-0943).
- Kogilavanee Devasvaran, Jun Jie Tan, Chin Theng Ng, Lai Yen Fong, Yoke Keong Yong, "Malaysian Tualang Honey Inhibits Hydrogen Peroxide-Induced Endothelial Hyperpermeability", Oxidative Medicine and Cellular Longevity, Hindawi, Volume 2019, pp 1-10, August 2019 (ISSN: 1942-0900).
- CT Ng, LY Fong, YK Yong, MN Hakim, Z Ahmad, "Interferon-γ induces biphasic changes in caldesmon localization as well as adherens junction organization and expression in HUVECs", CYTOKINE, Elsevier, Volume 111, pp 541-550, July 2018 (ISSN: 1043-4666).
- LY Fong, CT Ng, YK Yong, MN Hakim, Z Ahmad, "Asiatic acid stabilizes cytoskeletal proteins and prevents TNF-α-induced disorganization of cell-cell junctions in human aortic endothelial cells.", VASCULAR PHARMACOLOGY, Elsevier, Volume 117, pp 15-26, August 2018 (ISSN: 1537-1891).
- Ng CT, Fong LY, Tan JJ, Rajab NF, Yong YK, "Water extract of Clinacanthus nutans leaves exhibits in vitro, ex vivo and in vivo anti-angiogenic activities in endothelial cell via suppression of cell proliferation", BMC Complementary and Alternative Medicine, Springer, Volume 18, pp 210, July 2018 (ISSN: 1472-6882).
- Khairudin, N.N.H., Nurfarahdilla, Z, Ng, C. T., Fong, L. Y., Zuraini, A., "Experimental Review on the Substance P-Enhanced Endothelial Permeability in Human Umbilical Vein Endothelial Cells (HUVECS)", International Research Journal of Education and Sciences, Malaysia Association of Research and Education for Educators, Volume 1, Issue 2, pp 28-34, October 2017 (ISSN: 2550-2158).
- LY Fong, CT Ng, MN Hakim, Z Ahmad, "Barrier protective effect of asiatic acid in TNF-alpha-induced activation of human aortic endothelial cells", Phytomedicine, Elsevier, Volume 23, pp 191-199, January 2016 (ISSN: 0944-7113).
- CT Ng, LY Fong, YY Low, MN Hakim, Z Ahmad, "Nitric oxide participates in IFN-gamma-induced HUVECs hyperpermeability", Physiological Research, Institute of Physiology, Czech Academy of Sciences, Czech Republic, Volume 65, pp 1503-1508, August 2016 (ISSN: 0862-8408).
- Z Ahmad, CT Ng, LY Fong, GC Ee, MN Hakim, "Cryptotanshinone inhibits TNF-alpha-induced early atherogenic events in vitro", The Journal of Physiological Sciences, Springer, Volume 66, pp 213-220, May 2016 (ISSN: 1880-6562).
- CT Ng, LY Fong, MR Sulaiman, MN Hakim, Z Ahmad, "Interferon-Gamma Increases Endothelial Permeability by Causing Activation of p38 MAP Kinase and Actin Cytoskeleton Alteration", Journal of Interferon and Cytokine Research, Mary Ann Liebert, Inc, Volume 35, pp 513-522, July 2015 (ISSN: 1079-9907).
- LY Fong, CT Ng, ZA Zakaria, Ahmad Z, "Asiaticoside Inhibits TNF-alpha-Induced Endothelial Hyperpermeability of Human Aortic Endothelial Cells", Phytotherapy research, Wiley Blackwell, Volume 29, pp 1501-1508, July 2015 (ISSN: 1099-1573).
conference proceedings
- LY Fong, NN Mohd Razali, CT Ng, YK Yong, MN Hakim, Asiatic acid inhibits pro-oxidant mediators-induced oxidative stress in human aortic endothelial cells., PLANTA MEDICA, December 2022 (ISSN: 0032-0943).
- Tan BC, Gan QF, Foo CN, Leong PP, Physical Activity Status Among Pre-schoolers in Kajang Requires Attention!, The 2nd Biennial Medical & Health Sciences Conference 2019, UTAR Sg Long Campus, 4-6 July 2019 (ISBN: 0126-8635).
- YK Yong, CT Ng, LY Fong, NF Rajab, Anti-angiogenic effect of water extract from the Clinacanthus nutans leaves, Abstracts of The 76th Annual Meeting of the Japanese Cancer Association, Yokohama, Japan, 16 January 2018 (ISSN: 1347-9032).
- Lai Yen Fong, Chin Theng Ng, Zuraini Ahmad, Asiatic acid inhibits TNF-α-induced diphospho-myosin light chain (MLC) redistribution and structural remodeling of adherens junctions in human aortic endothelial cells (HAECs), Proceedings of The 95th Annual Meeting of the Physiological Society of Japan, Kagawa, Japan, 5 May 2018 (ISSN: 1880-6546).
book chapter
- Ng CT, Mah SH, Fong LY, Ancient and Traditional Foods, Plants, Herbs and Spices Used in Cardiovascular Health and Disease, CRC Press/Taylor's and Francis, 2023 (ISBN: 9781003220329).