Prof. Dr Alan Ong Han Kiat
journal article
- Ahmed Faris Aldoghachia, Jit-Kai Loh, Mong-Lien Wang, Yi-Ping Yang, "Current developments and therapeutic potentials of exosomes from induced pluripotent stem cells derived mesenchymal stem cells", Journal of the Chinese Medical Association, Wolter's Kluwer, Volume 86, Issue 4, pp 356-365, April 2023 (ISSN: 1726-4901).
- Ahmed Faris, Aldoghachi, Zhi Xiong, Chong, Swee Keong, Yeap, Soon Keng, Cheong, Wan Yong, Ho, "Stem Cells for Cancer Therapy: Translating the Uncertainties and Possibilities of Stem Cell Properties into Opportunities for Effective Cancer Therapy", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, MDPI, Volume 24, Issue 2, pp 1-20, January 2023 (ISSN: 1422-0067).
- Zhi Xiong Chong, Chean Yeah Yong, Alan Han Kiat Ong, Swee Keong Yeap, Wan Yong Ho, "Deciphering the roles of aryl hydrocarbon receptor (AHR) in
regulating carcinogenesis", TOXICOLOGY, Elsevier, Volume 495, pp 1-25, July 2023 (ISSN: 0300-483X).
- Ling, Lloyd, Ahmed Faris, Aldoghachi, Zhi Xiong, Chong, Wan Yong, Ho, Swee Keong, Yeap, "Addressing the Clinical Feasibility of Adopting Circulating
miRNA for Breast Cancer Detection, Monitoring and
Management with Artificial Intelligence and Machine
Learning Platforms", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, MDPI, Volume 23, pp 1-18, December 2022 (ISSN: 1422-0067).
- Loh Jit Kai, Wang Mong-Lien, Cheong Soon-Keng, "The Study of Cancer Cell in Stromal Environment through iPSC derived Mesenchymal Stem Cells", Journal of the Chinese Medical Association, Walters Kluwer, Volume 85, Issue 8, pp 821-830, August 2022 (ISSN: 1726-4901).
- Yap, M.L., Ong, H.K.O., Neela, V.K, Chee, H.Y, "Distribution of pathogenic Leptospira in environmental
water and soils of selected recreational forests in Perak, Malaysia", TROPICAL BIOMEDICINE, MSPTM, Volume 38, Issue 2, pp 122-128, June 2021 (ISSN: 0127-5720).
- Chong ZX, "Single-cell RNA sequencing in human lung cancer: Applications, challenges and pathway towards personalized therapy.", Journal of the Chinese Medical Association, Wolters Kluwer, Volume 84, pp 563-576, March 2021 (ISSN: 1726-4901).
- Chao-Yu Liu, "Molecular target therapeutics of EGF-TKI
and downstream signaling pathways in non-small
cell lung cancers", Journal of the Chinese Medical Association, Wolters Kluwer, Volume 85, pp 409-413, September 2021 (ISSN: 1726-4901).
- Swee Keong Yeap, Norlaily Mohd Ali, "Induction of Apoptosis and Regulation ofMicroRNA Expression
by (2E,6E)-2,6-bis-(4-hydroxy-3-methoxybenzylidene)-
cyclohexanone (BHMC) Treatment on MCF-7 Breast
Cancer Cells", MOLECULES, MDPI, Volume 26, Issue 1277, pp 1-15, February 2021 (ISSN: 1420-3049).
- Norlaily Mohd Ali, Swee Keong Yeap, Wan Yong Ho, Lily Boo, Huynh Ky, "Adipose MSCs Suppress MCF7 and MDA-MB-231 Breast
Cancer Metastasis and EMT Pathways Leading to Dormancy via Exosomal-miRNAs Following Co-Culture Interaction", Pharmaceuticals, MDPI, Volume 14, Issue 8, pp 1-29, December 2020 (ISSN: 1424-8247).
- Boo Lily, Cheong Soon Keng, Yeap Swee Keong, "Phenotypic and microRNA characterization of the neglected CD24+ cell population in MCF-7 breast cancer 3-dimensional spheroid culture", Journal of the Chinese Medical Association, Wolters Kluwer, Volume 83, Issue 1, pp 67-76, January 2020 (ISSN: 1726-4901).
- Shwe Sin, Ong HK, Boo NY, Seok CC, Jabbar MA, "Uridine Diphosphate Glucuronosyltransferase 1A1 (UGT1A1) Gene Polymorphisms in Indian Malaysian Newborns with Significant Neonatal Hyperbilirubinemia. IOSR Journal of Dental and Medical Sciences", IOSR Journal of Dental and Medical Sciences, International Organization Of Scientific Research (IOSR), Volume 19, Issue 5, pp 44-49, May 2020 (ISSN: 2279-0853).
- Sin SHWE, Nem-Yun BOO, Han-Kiat ONG, Seok-Chiong CHEE, Mohamed MASLINA, "Haemoglobin Constant Spring (HbA2: c.427T>C) and Haemoglobin Adana (HbA2: c.179G>A) in jaundiced Malaysian term neonates with clinically significant hyperbilirubinemia", Malaysian Journal of Pathology, College of Pathologists, Academy of Medicine Malaysia, Volume 42, Issue 2, pp 253-257, August 2020 (ISSN: 0126-8635).
- Nem-Yun Boo,, Shwe Sin,, Seok-Chiong Chee, Maslina Mohamed, Anita Kaur Ahluwalia, "Genetic Factors and Delayed TSB Monitoring and Treatment as Risk Factors Associated with Severe Hyperbilirubinemia in Term Neonates Admitted for Phototherapy", Journal of Tropical Pediatrics, Oxford University Press, pp 1-10, June 2020 (ISSN: 1465-3664).
- Nalini Devi Verusingama, Yi-Chen Chen, Heng-Fu Lin, Chao-Yu Liu, Ming-Cheng Lee, "Generation of Osimertinib-Resistant Cells from EGFR L858R/T790M Mutant NSCLC
Cell Line", Journal of the Chinese Medical Association, Wolters Kluwer, September 2020 (ISSN: 1726-4901).
- Shwe Sin, Ong Han Kiat, Alan, "Anti-RO/SS-A Antibody-Associated Autoimmune Vasculitis:
Case Report", IOSR Journal of Dental and Medical Sciences (IOSR-JDMS), International Organisation of Scientific Research (IOSR), Volume 18, Issue 9, pp 89-92, September 2019 (ISSN: 2279-0861).
- P.-F. Choong,, H.-X. Teh, H.-K. Teoh, Cheong SK, "DNA repair efficiency associated with reprogrammed
osteosarcoma cells", Gene Reports, Elsevier, Volume 16, pp 1-10, May 2019 (ISSN: 2452-0144).
- Yap May Ling, "Comparative analysis of current diagnostic PCR assays in detecting pathogenic Leptospira isolates from environmental samples", Asian Pacific Journal of Tropical Medicine, Wolters Kluwer- Medknow, Volume 12, Issue 10, pp 472-478, October 2019 (ISSN: 1995-7645).
- Wong Boon Yee, Taranjeet Kuar, Gideon Khoo, "Intra- and Inter-specific Variation of Four Acetes Species (Crustacea: Decapoda: Sergestidae) Sampled along the West Coast of Peninsular Malaysia", Sains Malaysiana, UKM PRESS, Volume 46, Issue 12, pp 2393-2416, January 2018 (ISSN: 1026-6039).
- Boo Lily, Cheong Soon Keong, Yeap Swee Keong, Ho Wan Yong, "Phenotypic and microRNA transcriptomic profiling of the MDA-MB-231 spheroid-enriched CSCs with comparison of MCF-7 microRNA profiling dataset", PeerJ, PeerJ Inc, Volume 5, Issue e3551, pp 1-27, July 2017 (ISSN: 2167-8359).
- Nalini Devi Verusingam, Cheong Soon Keng, "Susceptibility of Human Oral Squamous
Cell Carcinoma (OSCC) H103 and H376
cell lines to Retroviral OSKM mediated
reprogramming", PeerJ, PeerJ, Inc, Volume 5, pp 1-17, April 2017 (ISSN: 2167-8359).
- Mok Shao Feng, Yap Sook Fan, "The oral microbiome community variations associated with
normal, potentially malignant disorders and malignant lesions
of the oral cavity", Malaysian Journal of Pathology, Malaysian Journal of Pathology, College of Pathologist, Volume 39, Issue 1, pp 1-15, April 2017 (ISSN: 0126-8635).
- Norlaily Mohd Ali, Han Kiat Alan‑Ong, "Synthetic curcumin derivative DK1
possessed G2/M arrest and induced apoptosis
through accumulation of intracellular ROS
in MCF‑7 breast cancer cells", Cancer Cell International, BIOMED CENTRAL LTD, Volume 17, Issue 30, pp 1-12, February 2017 (ISSN: 1475-2867).
- Norlaily Mohd Ali, Yeap Swee Keong, "Flavokawain deriative FLS induced G2/M arrest and apoptosis on breast cancer MCF-7 cell line", Drug Design, Development and Therapy, Dovepress, Volume 10, pp 1-11, April 2016 (ISSN: 1177-8881).
- Lim Sheng Jye, "Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for in vitro hair follicle
cloning", PeerJ, PeerJ Inc, Volume 4, pp 1-17, November 2016 (ISSN: 2167-8359).
- Norlaily Mohd Ali, Lily Boo, Swee Keong Yeap, Soon Keng Cheong, Tunku Kamarul, "Probable impact of age and hypoxia on proliferation and microRNA expression profile of bone marrow-derived human mesenchymal stem cells", PeerJ, PeerJ, pp 1-19, January 2016 (ISSN: 2167-8359).
- Lily Boo, Wan Yong, Ho, Swee Keong Yeap, Soon Keng Cheong, "MiRNA Transcriptome Profiling of Spheroid-Enriched Cells with Cancer Stem Cell Properties in Human Breast MCF-7 Cell Line", International Journal of Biological Sciences, Ivyspring International Publisher, Volume 12, Issue 4, pp 427-445, February 2016 (ISSN: 1449-2288).
- BehnamShafiei-Astani, "Molecular genetic variation and structure of Southeast Asian crocodile
(Tomistoma schlegelii): Comparative potentials of SSRs versus ISSRs", Gene, Elsevier, Volume 57, pp 107-116, August 2015 (ISSN: 0378-1119).
- Gideon Khoo, "Length-Weight Relationships of Acetes spp. Sampled Along the West Coast of
Peninsular Malaysia", Sains Malaysiana, Penerbit UKM, Volume 44, Issue 3, pp 379-386, March 2015 (ISSN: NIL).
- Kok Hong Tan, Fah Choy Chia, Alan Ong Han Kiat, "Impact of Swiftlet's Moult Season on the Value of Edible Bird Nests", International Proceedings of Chemical, Biological and Environmental Engineering (IPCBEE), International Association of Computer Science and Information Technology Press (IACSIT Press), Volume 63, Issue 4, pp 17-21, February 2014 (ISSN: 2010-4618).
- Swan SL, Gideon Khoo, Thomas Smith, "Molecular Diversity of the Methanotrophic Bacteria Communities associated with Disused Tin-Mining Ponds in Kampar, Perak, Malaysia", World Journal of Microbiology and Biotechnology (WIBI), Springer, Volume 30, Issue 10, pp 2645-2653, June 2014 (ISSN: 0959-3993).
- LK Chong, SG Tan, KAS Taranjeet, MM Peris, HR Hassan, "Morphological and Genetic Variations
of the Freshwater Leech, Hirudinaria spp.,
in Peninsular Malaysia", Biochemical Genetics, Springer, Volume 52, pp 283-289, February 2014 (ISSN: 0006-2928).
- Choong Pei Feng, Teh Hui Xin, Teoh Hoon Koon, Ong Han Kiat, Alan, Cheong Soon Keng, "Heterogeneity of Osteosarcoma Cell Lines Led to
Variable Responses in Reprogramming", International Journal of Medical Sciences, Ivyspring International Publisher, Volume 11, Issue 11, pp 1154-1160, August 2014 (ISSN: 1449-1907).
- Taranjeet Kaur, J. R. R. Japning, M. S. Sabki, I. Sidik, L. K. Chong, "Genetic Diversity of Tomistoma schlegelii Inferred
from mtDNA Markers", Biochemical Genetics, Springer, Volume 51, Issue 3/4, pp 275-295, April 2013 (ISSN: 0006-2928).
- Loh Jiun Yan, Hii Yii Siang, Thomas J. Smith, Malcolm M. Lock, Gideon Khoo, "Impact of Potential Food Sources on the Life Table of Cladoceran, Moina macrocopa.", The Israeli Journal of Aquaculture ? Bamidgeh, ISRAELI JOURNAL OF AQUACULTURE-BAMIDGEH, Volume 65, pp 820-828, January 2013 (ISSN: 0792-156X).
- S. L. S. Sow, G. Khoo, L. K. Chong, T. J. Smith, P. L. Harrison, "Molecular diversity of the ammonia-oxidizing bacteria community in disused tin-mining ponds located within Kampar, Perak, Malaysia", World Journal of Microbioloby and Biotechnology, Springer, Volume 30, Issue 2, pp 757-766, September 2013 (ISSN: 0959-3993).
- Seng HL, Ng CH., "Biological and cytoselective anticancer properties of copper(II)-polypyridyl complexes modulated by auxiliary methylated glycine ligand.", Biometals, Springer, Volume 25, Issue 5, pp 1061-1081, October 2012 (ISSN: 0966-0844).
- K. Chinna, S.K. Khoo, W.L. Ng, L.K. Chong, K. Pillai, "Morphometric Sex Determination
of Milky and Painted Storks in Captivity", Zoo Biology, Wiley, Volume 31, Issue 2, pp 219-228, March 2012 (ISSN: 0733-3188).
- Loh Jiun Yan, Hii Yii Siang, Thomas J. Smith, Malcolm W. Lock, Gideon Khoo, "Highly Unsaturated Fatty Acid (HUFA) Retention in the Freshwater Cladoceran, Moina macrocopa, Enriched With Lipid Emulsions", The Israeli Journal of Aquaculture - Bamidgeh, IJA, Society of Isreali Aquaculture, Volume 64, pp 637-646, May 2012 (ISSN: 0792-156X).
- Taranjeet Kaur, "Heteroplasmy, Length, and Sequence Characterization of the Mitochondrial Control Region
in Tomistoma schlegelii", Biochemical Genetics, Springer, Volume 49, pp 562-575, April 2011 (ISSN: 0006-2928).
- Loh J.Y., How C.W., Hii Y.S., Khoo G., Ong H.K.A., "Fish Faeces as a potential Food Source for Cultivating the Water flea, Moina Macrocopa", Journal od Science and Technology in The Tropics, Akademi Sains Malaysia/COSTAM, Volume 5, pp 5-10, June 2009 (ISSN: 1823-5034).
- Hoi-Ling Seng, Han-Kiat Alan Ong, Raja Noor Zaliha Raja Abd. Rahman , Bohari M. Yamin, Edward R.T. Tiekink, Kong Wai Tan, Mohd Jamil Maah , Ignez Caracelli , Chew Hee Ng., "Factors affecting nucleolytic efficiency of some ternary metal complexes with
DNA binding and recognition domains. Crystal and molecular structure of
Zn(phen)(edda)", Journal of Inorganic Biochemistry, Elsevier, Volume 102, pp 1997-2011, August 2008 (ISSN: 0162-0134).
- Ong HKA, Vellayan S., "An Evaluation of CHD-Specific Primer Sets for Sex Typing of Birds from Feathers", Zoo Biology, Wiley, Volume 27, Issue 1, pp 62-69, January 2008 (ISSN: 0733-3188).
- Chew Hee Ng, Han Kiat Alan Ong, Chiak Wu Kong, Kong Wai Tan, Raja Noor Zaliha Raja Abd. Rahman, Bohari M. Yamin, Seik Weng Ng, "Factors affecting the nucleolytic cleavage of DNA by (N,N0-ethylenendiaminediacetato)metal(II) complexes, M(edda). Crystal structure of Co(edda).", Polyhedron, Elsevier, Volume 25, pp 3118-3126, May 2006 (ISSN: 0277-5387).
- CHEW HEE NG, HAN KIAT ALAN ONG, KONG CHIAK WU,SU KOK KHIONG and SEIK WENG NG, "Synthesis, characterization and nucleolytic property of
bis(N,N??-dimethylglycinato)copper(II)", Journal of Co-ordination Chemistry, Taylor and Francis, Volume 59, Issue 10, pp 1089-1099, July 2006 (ISSN: 0095-8972).
- Ng C.H., Ong H.K.A, Ngai K.S., Tan W.T., Lim L.P., Teoh S.G. and Chong T.S., "mer-Tris(B-alaninato)cobalt(III): Crytal structure, solution properties and its DNA cleavage in the presence of ascorbic acid", Polyhedron (available in Sciencedirect.com), Elsevier, Volume 24, pp 1503-1509, March 2005 (ISSN: 0277-5387).
- A.M. Ali, A. R. Omar, K. Yusoff, "Cloning and expression of the HN gene from the velogenic viscerotropic
Newcastle disease virus strain AF2240 in Sf9 insect cells", Cytotechnology, Springer, Volume 32, pp 243-251, January 2000 (ISSN: 0920-9069).
- Tan CB, Poh LKS, Tan JAMA, Helen TJIA, Lee BW, "DNA amplification of the CTG repeat sequence in the molecular characterisation of Myotonic Dystrophy", Neurology Asia (Formerly known as Neurology Journal of South East Asia), ASEAN NEUROLOGICAL ASSOC, Volume 2, pp 177-183, February 1997 (ISSN: 1823-6138).
conference proceedings
- Jit-Kai Loh, Nalini Devi Verusingam, Fu-Ting Tsa,, Shu-Huei Huang, Mong-Lien Wang, P033 The establishment of iPSC derived MSC for regenerative study, Malaysian Journal of Pathology, April 2022 (ISSN: 0126-8635).
- Nalini Devi Verusingam¹, Ping-Hsing Tsai, Mong-Lien Wang, Shih-Hwa Chiou, Soon-Keng Cheong, CircularRNA (circRNA) expression profiles associated with Osimertinib resistance in EGFR L858R/T790M
mutant NSCLC cell line, Malaysian Journal of Pathology, April 2021 (ISSN: 0126-8635).
- Tan Eng Tiek, Dr. Hii Siew Ling, Dr. Gideon Khoo, Dr. Alan Ong, MOLECULAR CHARACTERISATION OF MICROBIAL COMMUNITIES ASSOCIATED
WITH LIVE FEED AND LARVAE CULTURE IN A COMMERCIAL FISH FARMING
SYSTEM, Proceedings of the National Postgraduate Seminar, Selangor, 30 December 2010 (ISSN: ).
- Swan Sow, Dr. Gideon Khoo, Dr. Chong Lee Kim, Dr. Alan Ong, MOLECULAR CHARACTERIZATION OF AMMONIA OXIDIZING BACTERIA (AOB) AND
METHANE OXIDIZING BACTERIA (MOB) IN DISUSED TIN-MINING PONDS LOCATED
WITHIN KAMPAR, PERAK, MALAYSIA, Proceedings of the National Postgraduate Seminar 2010, Selangor, 30 December 2010 (ISSN: ).
- Swan Sow, Dr. Gideon Khoo, Dr. Chong Lee Kim, Dr. Alan Ong, Molecular Characterization of Bacterial Communities in Disused Tin-Mining Ponds Located within Kampar, Perak, Malaysia, International Conference and Exhibition on the Rehabilitation, Restoration & Transformation of Mining Land, Sunway, 1 November 2010-3 November (ISSN: ).
- Alan, H.K.A., Chong, L.K., Vellayan, S., Khoo, S.K., Boo, L., Ng, Y.T., and Ng, W.W., Non-invasive DNA sex typing of Malaysian and Exotic Birds, Proceedings of KUSTEM 5th Annual Seminar on Sustainability Science and Management, 2-3 May 2006 (ISSN: ).
- H.K.A. Ong, Y.K. Tang, A.M. Ali, B.T. Tey and K. Yusoff, Thermostability analysis of Recombinant HN protein from NDV strain V4(QUE), V4(UPM)HR and AF2240, Malaysian Society of Molecular Biology and Biotechnology 2004 Scientific Conference, 1 July 2004 (ISSN: ).
book chapter
- Shih-Hwa Chio, Han Kiat Alan Ong, Shih-Jie Chou, A.F. Aldoghachi, Jit Kai Loh, Stem Cell In Medicine, Elsevier, 2023 (ISBN: 978-0-443-13411-1).
periodical/magazine
- Ong HKA (Universiti Tunku Abdul Rahman), LK Chong (Department of Chemistry, MOSTI) and S. Vellayan (Zoo Negara Malaysia), Implementing wildlife conservation efforts, breeding management and enforcement through DNA Science., Balai Ikhtisas Malaysia, 2006 (ISBN: NIL).
monograph
- Gideon Khoo, Swan Sow Lee, Uncultured ammonia-oxidizing beta proteobacterium 16S ribosomal RNA gene, partial sequence. National Center for Biotechnology Information (USA): (GenBank Accession Number: JX184132-JX184238) (107 sequences), National Centre for Biotechnology informtaion (NCBI), 2014 (ISBN: NIL).
- Gideon Khoo, Swan Sow Lee, Proteobacteria particulate methane monooxygenase subunit A (pmoA) gene, partial cds. National Center for Biotechnology Information (USA): (GenBank Accession Number: JX184239-JX184403) (165 sequences), National Centre of Biotechnology Information (USA), 2014 (ISBN: NIL).
- Kaur,T, Molecular characterization of the Malaysian leech, National Centre for Biotechnology information (NCBI) USA, 2013 (ISBN: NIL).
- Kuar TS, Hirudinaria cytochrome oxidase subunit I (COI) gene, partial cds; mitochondrial. (JQ738395-JQ738408), National Centre of Biotechnology Information, 2013 (ISBN: NIL).
- Kuar TS, Tomistoma schlegelii tRNA-Thr, tRNA-Pro, and tRNA-Phe genes, complete - PopSet (HM593977-HM594032), National Centre of Biotechnology Information (NCBI) USA, 2013 (ISBN: NIL).
- Kuar TS, Tomistoma schlegelii NADH dehydrogenase subunit 6 gene, partial cds; t - PopSet (HM594033-HM594088), National Centre of Biotechnology Information, 2013 (ISBN: NIL).
- Kuar TS, Tomistoma schlegelii control region, partial sequence; mitochondrial. - PopSet (GU220807), National Centre for Biotechnology Information (NCBI), USA, 2011 (ISBN: NIL).
- Kuar TS, Tomistoma schlegelii control region, partial sequence; mitochondrial. - PopSet (GQ421344-GQ421357), National Centre of Biotechnology Information (NCBI), USA, 2011 (ISBN: NIL).