Prof Ts Dr Lim Yang Mooi
Funding in UTAR
  • synthesis of new xanthone analogues and thier pharmacological activity (as co- researcher), MTSF, January 2009.
  • synthesis and cytotoxic activities of new xanthone analogues (e-science, mosti, 2009-2011; co-researcher), MOSTI SCIENCE FUND, May 2009.
  • bioassay-guided isolation and elucidation of active anti-tumour-promoting and antioxidant compound(s) of four selected local medicinal plants, IFS, SWEDEN, May 2008.
  • an assay development for detecting ganglioside expression in yac-1, a murine lymphoma cell line, UTARRF, March 2008 - March 2009.
  • an investigatin of the chemopreventive mechanisms of maslinic acid o pma-induced tumorigenesis, MOSTI SCIENCE FUND, October 2007 - March 2010.
  • inhibitory effect of active herbal phytochemicals isolated from stenochlaena palustri on ganglioside in ls 174t human colorectal adenocarcinoma cell line, UTARRF, June 2009 - December 2010.
  • molecular investigation of traditional chinese medicine on a selected cancerous cell via 2d-gel electrophoresis, UTARRF, January 2011 - December 2011.
  • 3d culture and expansion of human mesenchymal stem cells (hmsc) with novel microcarriers, UTARRF, July 2011 - June 2012.
  • a preliminary study on the effect of edible bird nest on the neuron stem cells, UTARRF, July 2011 - June 2012.
  • scaling up of borneol extraction via fractional distillation (second phase eys-utar borneol project), EYS, January 2012 - June 2013.
  • metabolic profiling on local edible bird's nest, UTARRF, July 2012 - June 2013.
  • evaluation of maslinic acid in inducing phase ii detoxifying/anti-oxidant enzymes via activation of nuclear factor erythroid-2 related factor (nrf2) signaling pathway in hepg2 cells, MOHE FRGS, January 2012 - December 2013.
  • 2-methoxy-1, 4 naphthoquinone (mnq) in regulating protein kinase c and its downstream signaling pathway, MOHE FRGS, January 2012 - December 2013.
  • thermosensitive microcarriers for non-invasive detachment of anchorage dependent human mesenchymal stem cell, UTARRF, February 2013 - January 2014.
  • identification and validation of the differential protein expression induced by ap extracts on colorectal cancer ls-174t, UTARRF, February 2013 - January 2014.
  • cytotoxic and anti-tumour promoting activity of targeted compounds from the exudates of dryobalanops aromatica, UTARRF, July 2013 - June 2014.
  • effect of edible bird nest on global gene expression and differentially expressed protein on human mesenchymal stem cells, ROYAL BIRD'S NEST, August 2013 - July 2014.
  • the effect of cratoxylum cochinchinense lour (cc) on global mrna gene expression in hepg2 liver cancer cells, UTARRF, January 2014 - December 2014.
  • a study on ferromagnetism coating onto gold nanoparticles and its effect on bone and lung cancer cells, MOHE FRGS, December 2013 - November 2015.
  • decoding the differentiation of mesenchymal stem cells to mesangial cells at transcriptomic level, MTSF, January 2015 - December 2015.
  • validation of the differentially expressed genes and proteins in mesenchymal stem cells induced by edible bird nest, UTARRF, February 2015 - January 2016.
  • validation of the differentially expressed genes and proteins in hepg2 induced by cratoxylum cochinchinense lour (ccl), UTARRF, February 2015 - January 2016.
  • effect of ebn on immune system in vitro, DVS/PEMUDA, May 2014 - April 2016.
  • the protective effect of edible bird's nest on lrrk 2 (g2385r) variant-induced susceptibility to apoptosis and oxidative stress in parkinsonian neurodegenerative cell model, UTARRF, May 2016 - April 2017.
  • malaysian medicinal plants identification: illustration and metabolic fingerprinting, UTARRF, May 2016 - April 2017.
  • cytotoxicity evaluation on lpr-1 against a panel of cancer cell lines, LINK (THM) SCIENCES, SINGAPORE, June 2016 - May 2017.
  • effect of edible bird?s nest on human immunity, ROYAL BIRD NEST COMPANY, December 2016 - November 2017.
  • development of lab on a chip (loc) system to extract and study the characteristic of isolated exosome from nasopharyngeal carcinoma cell for early diagnostic of nasopharyngeal cancer (npc), UTARRF, December 2017 - January 2018.
  • screening the toxicity of zinc oxide nanoparticles in nutritional supplement microalgae hematococcus pluvialis, UTARRF, June 2017 - May 2018.
  • malaysian medicinal plants identification: illustration and metabolic fingerprintting (part ii), UTARRF, June 2017 - May 2018.
  • a multiplexd gene expression study on nasopharyngeal carcinoma treated with xiao xian xiong decoction, UTARRF, June 2017 - May 2018.
  • the neuroprotective effects of edible bird?s nest on oxidative stress-mediated damage in neuronal sh-sy5y cells, UTARRF, June 2017 - May 2018.
  • immunophenotyping for differentiation of monocytes into dendritic cells in modular immune in vitro construct (mimic) model, UTARRF, December 2018 - December 2018.
  • therapeutic effect of edible bird nest aqueous extract on crispr-cas9 system generated cell model for parkinson's disease with lrrk2 mutation (g2385r variant), MOA-DVS EPP, January 2018 - June 2019.
  • impact of titamium dioxide and silver nanoparticles on the nutritional properties of spirulina platensis, UTARRF, June 2019 - May 2020.
  • concurrent use of herbs to self-management of hypertensioin among adults living in kinta valley, perak, UTARRF, August 2020 - July 2020.
  • genetic and proteomic biomarkers for body constitution : as a predictive approach for detecting depression among utar students in sg long campus, UTARRF, December 2019 - December 2020.
  • evaluation of maslinic acid treatment efficacy in nod scid gamma (nsg) mice with colorectal cancer xenografts and transcriptomics profiling, MOHE FRGS, January 2019 - December 2020.
  • investigation of the effects of asiatic acid on pre-lesional atherogenic events in vitro and atherosclerotic lesion formation in vivo, MOHE FRGS, January 2019 - December 2020.
  • effectiveness and safety evaluation of beauty grade device onedoc picopulsetm for the treatment of melasma among malaysian women, ONEDOC SDN BHD, December 2020 - December 2021.
  • investigating the therapeutic potential of edible bird?s nest extract in lkkr2 associated (g2019s variant) parkinson?s disease, UTARRF, July 2021 - June 2022.
  • analysis of signs of palpation guided acupuncture using bioelectricity and ultrasonography, HAN NEURO ACUPUNCTURE & HERBAL SPECIALISTS SDN BHD, September 2021 - August 2022.
  • ambulatory blood pressure monitoring and poinbt-of care technology measurements for hypertensive adults integrating herbs, UTARRF, December 2021 - December 2022.
  • effects of epigallocaechin-3-gallate in restoration of insulim resistance, hyperglycaemia, and dyslipidaemia in a rodent model, UTARRF, December 2021 - December 2022.
  • genetic biomarkers as a predictive approach for detecting depression among utar students in sungai long campus, UTARRF, July 2022 - June 2023.
  • evaluation of effect of a new xanthone derivative, 3- phenylbutylxanthone, on tnf-α-induced endothelial activation, UTARRF, July 2022 - June 2023.
  • integration of traditional chinese medicine body constitutions in health determination among female reproductive cancer patients, MOHE FRGS, September 2021 - August 2023.
  • generation of lrrk2 knockout neuroblastoma cells using crispr/cas9 genome editing tool, UTARRF, December 2022 - December 2023.
  • evaluation of maslinic acid treatment efficacy in breast cancer xenografts and transcriptomics profiling, QUILINIQ LIFESCIENCE SDN BHD, July 2021 - June 2024.
  • a systematic approach to study the traditional chinese medicine as an adjuvant treatment in breast cancer patients, HAI-O- ENTERPRISE FOUNDATION RESEARCH FUND, June 2020 - July 2024.
  • modulatory effects of supercritical fluid-carbon dioxide-extracted malaysian kelulut propolis in mitigation of insulin resistance, hyperglycaemia, dyslipidaemia in a rat model of type 2 diabetes mellitus, MOHE FRGS, September 2022 - August 2024.
Funding not in UTAR
  • investigation key proteins and signaling pathways affected by the natural ctytotoxic compound 2-methoxy-1,4- naptoquinone in human cancer cell lines, TAYLORS' UNIVERSITY, August 2010 - July 2012.
  • elucidating the mechanisms of action of 2-methoxy-1,4-naphthoquinone (mnq) in mediating cell cycle arrest, apoptosis and anti-metastasis in human cancer cell lines, MOHE FRGS, September 2011 - August 2013.
  • elucidating the molecular mechanism of the interaction between maslinic acid and selected phospholipase a2 and its effects in regulating inflammation response, TAYLOR'S UNIVESITY, April 2014 - May 2015.
  • development of combination therapies targeting breast cancer stem cells, MOHE ERGS, June 2013 - May 2016.
  • transcriptomics study of the methyl-d-erythritol 4-phosphate (mep) biosynthesis pathway in impatiens balsamina l., MOHE FRGS, January 2015 - December 2017.
  • evaluating the mechanism of maslinic acid in monocyte recruitment and foam cell macrophage f nf­κb and nrf2, MOHE FRGS, August 2015 - July 2018.
  • monitoring and evaluation of covid-19 epidemic, CHINA CDC GRANT, July 2022 - June 2024.
  • establishment of in vitro cell-based model to study il-23/il-23r signalling pathway in enhancing t-cell proliferation, MOHE FRGS, September 2022 - August 2024.